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Use of the molecular adsorbents recirculating system as a treatment for acute decompensated wilson disease.

Liver Transpl. 2008 Sep 29;14(10):1512-1516Chiu A, Tsoi NS, Fan ST.

Intensive Care Unit, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.

Acute decompensated Wilson disease presenting as fulminant liver failure is a life-threatening condition for which liver transplantation is the ultimate treatment. It is listed as a status 1 indication according to the United Network for Organ Sharing classification. A massive amount of copper released during the attack induces hemolytic anemia and acute renal failure.

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Serum albumin level as a predictor of outcome in traumatic brain injury: potential for treatment.

J Trauma. 2008 Apr;64(4):872-5.

Bernard F, Al-Tamimi YZ, Chatfield D, Lynch AG, Matta BF, Menon DK.

University Department of Critical Care Medicine, Hôpital du Sacré-Coeur, Montréal, Québec, Canada. This e-mail address is being protected from spambots. You need JavaScript enabled to view it

BACKGROUND: Serum albumin level is correlated with outcome in various clinical situations. Albumin has multiple physiologic properties that could be beneficial in brain injury. The Lund therapy for elevated intracranial pressure uses albumin as part of its protocol and demonstrates favorable outcome. We sought to find out if albumin is associated with outcome after traumatic brain injury to justify conducting a randomized trial. METHODS: A retrospective study of traumatic brain injury patients was conducted. Characteristics known to influence outcome were included in a multiple logistic regression model to analyze predictors of poor outcome at 6 months.

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