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Association between ischemia modified albumin, inflammation and hyperglycemia in type 2 diabetes mellitus.
Clin Biochem. 2009 Dec 4
Kaefer M, Piva SJ, De Carvalho JA, Da Silva DB, Becker AM, Coelho AC, Duarte MM, Moresco RN.
Programa de Pós-Graduação em Ciências Farmacêuticas, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil; Laboratório de Bioquímica Clínica, Departamento de Análises Clínicas e Toxicológicas, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Objectives: The aim of this study was assess serum ischemia modified albumin (IMA) in type 2 diabetes patients and determine its correlation with other risk factors for chronic complications such as inflammation and hyperglycemia. Design and Methods: Fasting glucose, glycated albumin, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, creatinine, uric acid, albumin, lactic acid, high-sensitivity C reactive protein (hs-CRP) and IMA were measured in 80 patients with type 2 diabetes and 26 controls.
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Extracorporeal albumin dialysis.
Hepatol Res. 2008 Nov;38
Rifai K.
Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Patients
with liver failure still present a high mortality. It can only be
significantly improved by the rare resource of liver transplantation.
Extracorporeal liver support devices have been developed to temporarily
support liver detoxification. Artificial devices without hepatocytes
("liver dialysis" or "albumin dialysis") are already widely used in
Europe. The two best-known systems, MARS and Prometheus, use a
different technical approach to remove water-soluble as well as
albumin-bound toxins from the blood. In MARS, toxins diffuse along a
concentration gradient through an albumin-impermeable membrane into a
secondary circuit that is pre-filled with an albumin solution. The
albumin is continuously "recycled" inside the secondary circuit by
different adsorber and low flux dialysis.
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